As coordinators of the Global Mental Health Working Group of the Global Health Hub Germany (GHHG), we combine experience and expertise across a wide network of members from different disciplines and societal sectors. Our recommendations in this paper are aimed at national and international health policy makers. In addition, other stakeholders, such as health organisations, health insurance companies, professional organisations, hospitals, practising physicians, non-governmental organisations and patient associations are important for systemic development and implementation. An integrative approach through a biopsychosocial model will help understand and alleviate the psychological stress of Covid-19.